The MassARRAY® System is an open platform that streamlines genetic analysis with broad genetic coverage, rapid processing, and clear data analysis. Available in both 96 and 384-well plate formats with the ability to expand across multiple applications, the system enables labs to focus on a select set of gene regions that have known or emerging associations with diseases. A broad menu of robust chemistries allows genotyping, somatic mutation detection, and quantitative analysis all on a single platform.
The MassARRAY System workflow couples mass spectrometry with end-point PCR, enabling highly multiplexed reactions under universal cycling conditions to provide rapid genetic analysis. After nucleic acid extraction, approximately 10-40ng of sample advances through a simple workflow with 3 easy steps:
Multiplex end-point PCR followed by a single base extension reaction
Automated analyte transfer and data acquisition
Data display and report generation
* Workflow time may vary depending on chemistry and acquisition settings.
The MassARRAY system can detect SNPs, insertions, deletions, translocations, copy number variation, and methylation markers allowing it to be used across a variety of research applications, including: