Rapidly analyze methylation status of 10s to 100s of research samples using the MassARRAY System.
MassCLEAVETM chemistry enables high-resolution, quantitative methylation profiling using base-specific cleavage on bisulfite-converted DNA. The high sensitivity of the MassARRAY System enables detection of differences as low as 5% between methylated and non-methylated DNA.
Custom panels for profiling CpG methylation can be designed using Agena’s EpiDesigner software. General reagents including bisulfite conversion kits are available to process samples for analysis on the MassARRAY System.
Excerpt from Quantitative Region-Specific DNA Methylation Analysis by the EpiTYPER Technology, DNA Methylation Protocols. Humana Press, NY NY, 2018
Assays by Agena scientists design and develop custom research use assays. Assays can be developed for targeted germline or somatic genotyping, translocations, copy number variants and methylation profiling.