Studies estimate 1 in every 200 samples is misidentified, potentially causing incorrect results. Labs implement rigorous quality systems to ensure chain of custody for specimens. However, specimen mishandling may occur at various steps, and these mistakes can result in incorrect care, damaging a lab’s reputation. Labs need robust sample identity tracking to prevent errors and ensure the results match the specimen.
Each of Agena’s Sample Integrity panels provide genetic fingerprinting to determine:
Verify identity by comparing genetic fingerprints. Prevent mistakes even if they originate outside the lab.
Automated analysis compares profiles to determine if a sample originated from the stated source. A built-in analysis algorithm accounts for loss of heterozygosity in tumor/normal comparisons.
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Assays by Agena scientists design and develop custom research use assays. Assays can be developed for targeted germline or somatic genotyping, translocations, copy number variants and methylation profiling.