VeriDose® CYP2D6 CNV Panel

Accurate CNV & hybrid allele detection that can be run side-by-side with genotyping panels

CYP2D6 copy number variation (CNV) detection is a critical aspect of PGx testing. However, not all CYP2D6 alleles are functionally similar. Depending on ethnicity, up to 45% of individuals possess non-functional CYP2D6/CYP2D7 “hybrid alleles” including exon 9 exchanges, *13 and *68. Many detection technologies cannot detect these alleles, resulting in sample mischaracterization.

The VeriDose CYP2D6 Panel accurately detects CNVs even in the presence of difficult to detect hybrid alleles. It interrogates 22 points in 7 regions of the CYP2D6 gene using a single well. This panel can be run simultaneously with genotyping panels, seamlessly integrating genotyping and CNV workflows.

Panel Resources
Ordering Information
Product # of Samples Format Catalog #
VeriDose CYP2D6 CNV Panel Set - CPM (1x96) 96 96 CPM 13180F
VeriDose CYP2D6 CNV Panel Set - CPM (5x96) 480 96 CPM 13179F
VeriDose CYP2D6 CNV Panel 2N Control 200 N/A 02005
VeriDose CYP2D6 CNV Panel Set - CPM (10x384) 3840 384 CPM 13256D
VeriDose CYP2D6 CNV Panel Set - CPM (2x384) 768 384 CPM 13255D

“ Bottom line, if you are detecting CNV by looking only at a specific region, you are likely missing hybrid alleles

– Dr. Houda Hachad

CSO, Translational Software

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